Current Practices of Treating Dementia and Alzheimer's Disease What are Cholinesterase Inhibitors? Cholinesterase inhibitors essentially work to increase the volume and activity of neurotransmitters to improve memory, thought and judgment in patients with early to moderate stages of degenerative dementia (Dementia medication, 2015). Alzheimer's disease and other forms of degenerative dementia have shown a decreased level of activity in the neurotransmitter acetylcholine, whic